Cheap flights from Knoxville to Sao Paulo

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Find the cheapest month to fly from Knoxville to Sao Paulo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Sao Paulo flights are currently cheapest in April.

Alternative Knoxville to Sao Paulo routes

Looking for the cheapest, fastest or easiest route from Knoxville to Sao Paulo? You could fly into the following airports instead.

Knoxville to Sao Paulo: Flight information

The things to know before you go.
Cheapest flight found$703
Cheapest month to flyApril

Finding cheap flights from Knoxville to Sao Paulo: Frequently asked questions

There are 4 airports in Sao Paulo: Sao Paulo Congonhas, Sao Paulo Guarulhos, Sao Paulo Viracopos, and Sao Jose Dos Campos.
The best price we found for a round-trip flight from Knoxville to Sao Paulo is $703. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Sao Paulo. But we found flights with one or more stops from $703.
There are no flights flying from Knoxville to Sao Paulo, as of March 2025.
The cheapest month to fly from Knoxville to Sao Paulo is usually March 2025.
If you're flying from Knoxville Airport, the cheapest airport near Sao Paulo is Sao Paulo Guarulhos – which is 20.4 km away from the center of Sao Paulo. We've found flights to this airport from $703.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Sao Paulo on Wednesday, April 23, 2025.
No airlines currently offer direct flights between Knoxville Airport and Sao Paulo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.
In March, the average temperature is usually around 23°C. February is typically the warmest month in Sao Paulo, when it usually averages around 27°C. You can expect the least rain in August. The coldest month is July, with temperatures averaging 12°C. The rainiest month is January.
Currently, Delta offers the cheapest flight tickets to Sao Paulo.

Flying from McGhee Tyson Airport (TYS) to Sao Paulo: what you need to know

  • McGhee Tyson Airport is located in Knoxville. Operating on the UTC-3 timezone, Sao Paulo is 1 hour ahead of Knoxville.

  • Leave plenty of time to make your flight from TYS to Sao Paulo. It's generally best to arrive two hours before international departures and an hour ahead for domestic flights.

  • If you're traveling during a peak month like July, make your way to the airport even earlier. It's wise to arrive up to four hours before an international flight and two hours ahead of a domestic departure. Security lines will be longer during vacation periods like spring break and summer.

  • You don't need a visa for Brazil if you have a passport from United States and are traveling for tourism purposes. Travel documentation and visa requirements can be subject to change. So before locking in your cheap tickets from McGhee Tyson Airport to Sao Paulo, check with your airline and your destination country's local embassy or consulate for the latest information.

  • TYS is approximately 23 kilometers from central Knoxville. If you're driving, catching a cab or ride-sharing from the center, it'll take 19 minutes or so to arrive, depending on the traffic.

  • Looking for a handy hotel near TYS? If you're catching an early flight from McGhee Tyson Airport to Sao Paulo, these stays will put you moments from your departure lounge:

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Sao Paulo

  • The best price we've seen for a one-way ticket from McGhee Tyson Airport to Sao Paulo is $343. The cheapest price for a return flight is $703. Remember fares may change due to demand at the time of booking.

  • To find cheap tickets from TYS to Sao Paulo, book as early as you can. Airlines generally offer lower prices when flights are first released.

  • The 'Whole month' tool shows you the cheapest tickets from McGhee Tyson Airport to Sao Paulo across the entire month. It's a great way to snap up a bargain if your travel dates are flexible.

  • Locking in a cheap ticket from TYS to Sao Paulo is easy with Price Alerts. All you need to do is set up one of these automatic alerts and we'll get in touch when the price has fallen.

  • Make the most of the filters to find your ideal trip. To see the 'Fastest,' 'Best' or 'Cheapest' flights from McGhee Tyson Airport to Sao Paulo, use the 'Sort by' tool. You can also filter results by arrival and departure times, airline, and journey duration.

Airports in Sao Paulo

Sao Paulo-Guarulhos International Airport (GRU)

  • Sao Paulo-Guarulhos International Airport (GRU) to the center of Sao Paulo takes about 32 minutes by car. It's approximately 26 kilometers away.

  • Getting to the center on public transport will take you roughly 1 hour and 22 minutes.

  • If you have a late flight from McGhee Tyson Airport to Sao Paulo, nothing beats the convenience of staying close to the terminal. Pick up your bags from the carousel and then be showered and snoozing soon after at one of these hotels near GRU:

Sao Paulo/Congonhas Airport (CGH)

  • The center of Sao Paulo is located around 10 kilometers from Sao Paulo/Congonhas Airport (CGH). After your flight from McGhee Tyson Airport to Sao Paulo has landed and you've made your way out of the airport, the drive should take about 17 minutes.

  • You can expect the journey to take approximately 34 minutes on public transport.

  • There are some great places to drop your things at near CGH. Settle in and get cozy after your flight from TYS to Sao Paulo at any of these well-located options:

Best time to go to Sao Paulo

  • It's time to choose your travel dates for your flight from McGhee Tyson Airport to Sao Paulo. July is the most popular month to visit Sao Paulo. If you want a more low-key vibe, go in May.

  • Before booking a flight from McGhee Tyson Airport to Sao Paulo, think about the type of weather you enjoy. February is the warmest month in Sao Paulo, with the temperature ranging from 18ºC to 28ºC.

  • If you like traveling in cooler conditions, search for a cheap flight from TYS to Sao Paulo in July when temperatures average between 12ºC and 25ºC.

More about Sao Paulo

Complete your Sao Paulo trip with a car rental

  • Finding you a cheap flight from McGhee Tyson Airport to Sao Paulo isn't the only thing we're good at. Check out our car rentals in Sao Paulo and see the sights your way. We search for deals from trusted car rental providers and put them all in one place. You can instantly compare offers and then book with no fees.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.