Cheap flights from Chicago to Panama City

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Flight deals from Chicago to Panama City

Looking for a cheap last-minute deal or the best round-trip flight from Chicago to Panama City? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Chicago to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago to Panama City flights are currently cheapest in May.

Direct flights from Chicago to Panama City

Alternative Chicago to Panama City routes

Looking for the cheapest, fastest or easiest route from Chicago to Panama City? You could fly into the following airports instead.

Chicago to Panama City: Flight information

The things to know before you go.
Cheapest flight found$400
Cheapest month to flyMay
Average flight time5 hrs, 28 mins
Most popular airlineCopa
Average flights per week36

Finding cheap flights from Chicago to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a round-trip flight from Chicago to Panama City is $399. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 28 minutes is the average flight time from Chicago to Panama City.
Copa, United and EVA Air fly direct from Chicago to Panama City.
There are 36 flights per week flying from Chicago to Panama City, as of March 2025.
The cheapest month to fly from Chicago to Panama City is usually March 2025.
If you're flying from Chicago, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the center of Panama City. We've found flights to this airport from $399.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Panama City on Sunday, May 11, 2025.
Yes – the average flight time is 5 hours and 28 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In March, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
The cheapest airline that flies to Panama City is Avianca, and the cheapest airline that flies to Balboa Airport is Copa.

Traveling from Chicago to Panama City: what you need to know

  • Chicago is home to two main airports where you can kick off your trip. Check out your options for booking a flight from Chicago to Panama City flying out of O'Hare International Airport (ORD) or Chicago Midway International Airport (MDW).

  • When planning your arrival in Panama City, Tocumen International Airport (PTY) and Panama Pacifico Airport (BLB) are the major hubs.

  • For a stress-free journey, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to catch your flight from Chicago to Panama City.

  • You can expect longer lines in popular months like August and other peak periods. Arriving up to four hours in advance for international flights and two hours for domestic departures is a good idea.

  • If you hold a passport from United States and plan to travel to Panama for tourism purposes, you won't need a visa. However, entry and visa requirements may differ based on your length of stay and are subject to change. For the latest information, contact your destination's nearest embassy or consulate before reserving a cheap flight from Chicago to Panama City.

Flying from Chicago

O'Hare International Airport (ORD)

  • If you're searching for a direct flight from Chicago to Panama City, they're available from O'Hare International Airport (ORD). Fly from ORD to Tocumen International Airport (PTY) in one continuous trip.

  • Copa Airlines is a leading airline that offers direct flights from Chicago to Panama City departing from ORD.

  • Think about adding a stopover to potentially save money on your flight from Chicago to Panama City. Just deselect 'Direct flights only' when browsing departures from O'Hare International Airport. Take a break (and maybe save some cash) by stopping at one of these airports:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Raleigh-Durham International Airport (RDU)

    • Miami International Airport (MIA)

  • ORD is around 40 kilometers from central Chicago. If you're driving, catching a cab or ride-sharing from the center, it'll take 35 minutes or so to get there, depending on traffic. If you're taking public transport, expect the journey time to be around 54 minutes.

  • Want an easy start to your journey? Stay near O'Hare International Airport. Whether you're boarding an early flight from Chicago to Panama City or just don't like being rushed, these hotels are the answer:

Chicago Midway International Airport (MDW)

  • Split up your flight from Chicago to Panama City with a stop so you can recharge or cross a new place off your list. Some great stopovers between O'Hare International Airport and Panama City include:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Raleigh-Durham International Airport (RDU)

    • Miami International Airport (MIA)

  • Using public transport, you can travel from central Chicago to MDW in around 46 minutes. The airport is roughly 19 kilometers away, and making the trip by car takes approximately 21 minutes.

  • Start your vacation sooner with an extra night away from home. Before catching your flight from Chicago to Panama City, take things easy in one of these hotels near Chicago Midway International Airport:

Arriving in Panama City

Tocumen International Airport (PTY)

Marcos A. Gelabert International Airport (PAC)

How to find the cheapest flights from Chicago to Panama City

  • The lowest price we've found for a one-way ticket from Chicago to Panama City is $132. For a return flight on this route, the best price is $399. Depending on when you want to go and the availability, these fares can change.

  • Don't leave everything to the last minute. You're more likely to find cheap tickets from Chicago to Panama City if you book early. Airlines often offer some amazing early bird deals.

  • Getting cheap tickets from Chicago to Panama City is easier if you can be flexible with your travel dates. Try using the 'Whole month' tool to see the best prices throughout the month and land a great deal.

  • Sign into your online account or use the app to set up a Price Alert. We'll let you know straight away if there's a cheaper deal on this route. It's simple to do, and it'll save you the hassle of looking for cheap tickets from Chicago to Panama City every day.

  • Take advantage of filters to find your ideal trip. To see the 'Fastest,' 'Best' or 'Cheapest' flights from Chicago to Panama City, use the 'Sort by' tool. You can also filter by airline, departure and arrival times, and journey duration.

Best time to go to Panama City

  • June is the most popular month for flights from Chicago to Panama City. To avoid the crowds, head to Panama City in February.

  • The warmest month in Panama City is March, with the temperature ranging between 21ºC and 32ºC. Lock in your flights from Chicago to Panama City in this month if this is the type of weather you enjoy.

  • Search for cheap tickets from Chicago to Panama City in February if you want to travel in cooler conditions. Temperatures are at their lowest around then, ranging between 22ºC and 31ºC on average.

More about Panama City

  • Start your Panama City trip off on the right foot by choosing the perfect place to stay. Once you've booked your flight from Chicago to Panama City, browse our range of accommodation options including:

  • There are so many things to explore in this city it can be hard to figure out where to begin. Panama Canal Museum, Casco Viejo and Cinta Costera are major attractions which should be on every Panama City itinerary.

Complete your Panama City trip with a car rental

  • We use the same magic that helped you find your cheap flight from Chicago to Panama City to track down incredible deals on car rentals. Search for your ride in seconds and easily compare your options. Plus we give you all the info you need to drive in Panama City, from the most popular car rental to the average daily price.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.