Flights from Madrid Airport to Brussels Capital Region

Travelers and cabin class

Flight deals from Madrid Airport to Brussels Capital Region

Looking for cheap flights from Madrid Airport to Brussels Capital Region, or a last-minute trip? Find the cheapest prices on one-way and round-trip flights right here.

Flying from Madrid Airport to Brussels Capital Region

Arm yourself with these facts on the fly.
Cheapest flight found$52, Brussels
Cheapest month to flyMay
Average flight time2 hrs, 24 mins
Average flights per week408
Most popular airlineLATAM Airlines

Frequently asked questions

Yes – direct flights currently operate from Madrid Airport to Brussels International Airport in Brussels Capital Region.
We looked at all of the upcoming round-trip flights from Madrid Airport to Brussels Capital Region we could find over the next 12 months. It looks like $52 is the best price. This is good, compared to the average Brussels Capital Region ticket price of $109.
The cheapest month to fly from Madrid Airport to Brussels Capital Region is currently May.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Madrid Airport to Brussels Capital Region on Thursday, May 29, 2025.
If you're flying from Madrid, the cheapest city in Brussels Capital Region to fly into is Brussels. The cheapest airport serving Brussels at the moment is Brussels International.
The average flight time between Madrid Airport and Brussels Capital Region is 2 hours and 23 minutes.